
中国科学院生物物理研究所,认知科学与心理健康全国重点实验室,研究组长
ORCID:0000-0001-8025-1552
谷歌学术:rpbBKksAAAAJ&hl
2007 - 2011 华中科技大学,学士
2011 - 2016 北京协和医学院/清华大学,博士
2016 - 2018 北京生命科学研究所,科研助理
2018 - 2021 美国冷泉港实验室,博士后
2021 - 2026 美国杜克大学,高级研究助理
2026 至今 中国科学院生物物理研究所,研究员
李毅研究组目前关注脑体信息交互与功能重建,结合高速行为动作追踪、大规模神经记录、感觉反馈操控、群体动力学建模和实时神经解码,研究大脑如何整合感觉反馈以产生精确、灵活的运动,并探索将这些原理转化为神经损伤后功能重建的策略。
1. Li Y, An X, Mulcahey PJ, Qian Y, Xu XH, Zhao S, Mohan H, Suryanarayana SM, Bachschmid-Romano L, Brunel N, Whishaw IQ, Huang ZJ (2026) Corticothalamic Communication for Action Coordination in a Skilled Motor Behavior. Nat. Neurosci. 29: 660-672. DOI: 10.1038/s41593-025-02195-8
2. An X, Li Y, Matho K, Mohan H, Xu X H, Boato F, Whishaw IQ, Huang ZJ (2026). A Cortical Circuit for Orchestrating Oromanual Food Manipulation. Neuron 114, 2254-2271 e9. DOI: 10.1016/j.neuron.2026.02.010
3. Li Y, Liu Z, Guo Q, Luo M (2019) Long-Term Fiber Photometry for Neuroscience Studies. Neurosci. Bull. 35, 425-433. DOI: 10.1007/s12264-019-00379-4
4. Li Y#, Zeng J#, Zhang J, Yue C, Feng Q, Zhong W, Liu Z, Luo M (2018). Hypothalamic Circuits for Predation and Evasion. Neuron 97: 911-924 e915. DOI: 10.1016/j.neuron.2018.01.005 [#equal contribution, cover, selected as Best of Neuron 2018 collection]
5. Lin R, Li Y, Luo M (2018). A Neural Circuit Driving Maternal Behaviors. Neuron 98, 6-8. DOI: 10.1016/j.neuron.2018.03.025
6. Zhong W#, Li Y#, Feng Q, and Luo M (2017). Learning and Stress Shape the Reward Response Patterns of Serotonin Neurons. Journal of Neurosci. 37, 8863-8875. DOI: 10.1523/JNEUROSCI.1181-17.2017 [*equal contribution]
7. Li Y, Zhong W, Wang D, Feng Q, Liu Z, Zhou J, Jia C, Hu F, Zeng J, Guo Q, Fu L, Luo M (2016). Serotonin Neurons in The Dorsal Raphe Nucleus Encode Reward Signals. Nat. Commun. 7, 10503. DOI: 10.1038/ncomms10503
8. Wang D, Li Y, Feng Q, Guo Q, Zhou J, Luo M (2017). Learning Shapes the Aversion and Reward Responses of Lateral Habenula Neurons. eLife 6. DOI: 10.7554/eLife.23045
9. Luo M, Li Y, and Zhong W (2016). Do dorsal raphe 5-HT neurons encode "beneficialness"? Neurobiol. Learn. and Mem. 135, 40-49. DOI: 10.1016/j.nlm.2016.08.008
10. Liu Z#, Zhou J#, Li Y, Hu F, Lu Y, Ma M, Feng Q, Zhang J, Wang D, Zeng J, Luo M (2014). Dorsal Raphe Neurons Signal Reward Through 5-HT and Glutamate. Neuron 81, 1360-1374. DOI: 10.1016/j.neuron.2014.02.010 [#equal contribution]
● Neural Dynamics Data Under Proprioceptive Distortion (2025) - Zenodo:
https://zenodo.org/records/17360954
● Code for OptoFP (2026) - GitHub:
https://github.com/liyistart/OptoFP_Imaging
● Behavior and Neuron Data during Reach to Consume (2025) - Duke:
https://doi.org/10.7924/r49k4mj1b
● Code for Reach-to-Consume Task (2025) - GitHub:
https://github.com/liyistart/PyN_Reach_to_Consume_Code
● Motor Cortex on Thalamic Spiking Dynamics (2025) - Figshare:
https://doi.org/10.6084/m9.figshare.27849483
● MultiCond App (2025) - GitHub:
https://github.com/liyistart/MultiCond
● Hand and Oral Movement Tracking Models (2023) - Zenodo:
https://doi.org/10.5281/zenodo.10041296
● Bonsai Workflow for Video Recording (2023) - Zenodo:
https://doi.org/10.5281/zenodo.10041374
● DRN Serotonin Neuron Data (2024) - Zenodo:
https://doi.org/10.5281/zenodo.13218589
(资料来源:李毅研究员,2026-08-20)
团队建设中,欢迎具有神经科学、工程、计算、医学等背景,并对脑科学具有兴趣的同学加入。