发表论文

(# First author, * corresponding author)

1. Zhang ZX^#, Chen C^#, Liu CY, Sun PK, Liu P, Fang S, Li XJ*. Isocyanic acid-mediated NLRP3 carbamoylation reduces NLRP3-NEK7 interaction and limits inflammasome activation. Science Advances 2025; 11(10): eadq4266

2. Chen C^#, Liu CY^#, Sun PK^#, Zhang ZX, Wang ZM, Liu P, Li XJ*. Itaconate uptake via SLC13A3 improves hepatic antibacterial innate immunity. Developmental Cell 2024; 59(21): 2807-2817

3. Chen C^#, Zhang ZX^#, Liu CY^#, Sun PK, Liu P, Li XJ*. ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis. Cell Metabolism 2024; 36(3): 498-510

4. Li X, Wang ZX, Chen C, Yang F, Liu P, Fang S, Wang B, Chen S*, Li XJ*. A small-molecule degrader selectively inhibits the growth of ALK-rearranged lung cancer with ceritinib resistance. iScience 2024; 27(2): 109015

5. Sun PK^#, Zhang ZX^#, Wang B, Liu CY, Chen C, Liu P, Li XJ*. A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages. Nature Communications 2022; 13(1): 6562

6. Chen C^#, Zhang ZX^#, Liu CY, Wang B, Liu P, Fang S, Yang F, You YP, Li XJ*. ATF4-dependent fructolysis fuels growth of glioblastoma multiforme. Nature Communications 2022; 13(1): 6108

7. Zhang ZX^#, Chen C^#, Yang F, Zeng Y-X, Sun PK, Liu P, Li XJ*. Itaconate is a lysosomal inducer that promotes antibacterial innate immunity. Molecular Cell 2022; 82(15): 2844-2857

8. Zhang ZX^#, Li X^#, Yang F^#, Chen C^#, Liu P, Ren Y, Sun PK, Wang ZX, You YP, Zeng Y-X, Li XJ*. DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis. Nature Communications 2021; 12(1): 5872

Invited Review

1. Chen C^#, Li XJ*. The cell autonomous and non-autonomous roles of itaconate in immune response. Cell Insight 2025; 4(1): 100224.

（资料来源：李新建研究员，2025-03-20）