Significance : Severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ) is a severe threat to public health and the global economy .Our study presents the in situ structure of the spike protein in the postfusion state with higher resolution , giving further insights into the design of a viral e...
Cryo-electron tomography ( cryo-ET ) provides a promising approach to study intact structures of macromolecules in situ , but the efficient preparation of high-quality cryosections represents a bottleneck .Two strategies were developed for loading cryo-lamella via a side-entry cryo-holder or an FEI A...
Structures of human mGlu2 and mGlu7 homo- and heterodimers
The Laboratory of Biological Electron Microscopy and Structural Biology(LBEMSB) is an individual research group with the principal investigator, Dr. Fei Sun. It belongs to the National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences (CAS). Besides, Dr. Sun also t...
