Clustering and multimerization of cell surface proteins (CSPs) are essential for triggering downstream intracellular signaling events. Membrane-anchored liquid–liquid phase-separation systems have now been developed to manipulate the spatiotemporal distribution and activation of CSPs.
最新重要论文
Gathering on the cell surface, Nat Chem Biol, 17 Nov 2022
Nature Chemical Biology, 17 November, 2022, DOI:https://doi.org/10.1038/s41589-022-01195-0
Gathering on the cell surface
Zheng Wang & Hong Zhang
Abstract
Clustering and multimerization of cell surface proteins (CSPs) are essential for triggering downstream intracellular signaling events. Membrane-anchored liquid–liquid phase-separation systems have now been developed to manipulate the spatiotemporal distribution and activation of CSPs.
文章链接:https://www.nature.com/articles/s41589-022-01195-0