1999-2003 清华大学生物系，博士
2003-2007 美国哈佛医学院，博士后
2007-2010 中科院生物物理研究所，副研究员
2010-2017 北京大学生命科学院，副研究员
2017至今 中科院生物物理研究所，高级工程师
（1）纳米酶新技术的开发与应用。
（2）CD146抗体在疾病诊断及治疗中的应用与转化；
1.Chen X*., Yan H*., Liu D., Xu Q., Duan H., Feng J., Yan X. and Xie C. Structure basis for AA98 Inhibition on the activation of endothelial cells mediated by CD146. iScience, 2021, https://doi.org/10.1016/j.isci.2021.102417
2.Zhang Y, Li Y, Zhang J, Chen X, Zhang R, Sun G, Jiang B, Fan K, Li Z, Yan X. Nanocage-Based Capture-Detection System for the Clinical Diagnosis of Autoimmune Disease. Small. 2021 Jun;17(25): e2101655.
3.Jiang B*, Chen X*, Sun G, Yin Y, Jin Y, Mi Q, Yang Y, Yan X, Fan K, A natural drug entry channel in the ferritin nanocage, Nano Today, 35, (2020), 100948
4.Liu D., Ju C., Han C., Shi R., Chen X., Duan D., Yan J. and Yan X. Nanozyme chemiluminescence paper test for rapid and sensitive detection of SARS-CoV-2 antigen, Biosensors and Bioelectronics, 173 (2021),112817
5.Wu Z, Liu J, Chen G, Du J, Cai H, Chen X, Ye G, Zhang L, Duan H, Yan X, Feng J, Bu P. et al. CD146 is a Novel ANGPTL2 Receptor that Promotes Obesity by Manipulating Lipid Metabolism and Energy Expenditure. Adv Sci (Weinh). 2021 Jan 27;8(6):2004032. doi: 10.1002/advs.202004032.
6.Duan H., Zhao S., Xiang J., Ju C., Chen X., Gramaglia I.and Yan X, Targeting the CD146/Galectin-9 axis protects the integrity of the blood–brain barrier in experimental cerebral malaria, Cellular & Molecular Immunology, 2020, https://doi.org/10.1038/s41423-020-00582-8
7.Zhang J., Chen X., Hong J., Tang A., Liu Y., Xie N., Nie G., Yan X. & Liang M. Biochemistry of mammalian ferritins in the regulation of cellular iron homeostasis and oxidative responses, Sci China Life Sci. 2020
8.阎锡蕴, 刘丹, 王大吉, 郝洪军, 段红霞, 刘铮, 陈雪晖, 冯静. 可溶性CD146作为血脑屏障损伤标志物在中枢神经系统疾病中的应用, 2018-09-28, 中国, 201811137822.9.
9.阎锡蕴,陈雪晖,晏荟文,刘丹,冯静,段红霞,徐庆吉.具有中和活性的抗人CD146单克隆抗体及其应用, 2020-4-10, 中国, 202010280682.1.
陈雪晖 高级工程师
研究方向：纳米酶新技术的开发与应用
电子邮件：chenxh@ibp.ac.cn
电 话：010-64888580
通讯地址：北京市朝阳区大屯路15号
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