国家"杰出青年基金"获得者 中国科学院生物物理研究所,脑与认知科学重点实验室,研究组长
1985 - 1989 南开大学物理系,获理学学士学位
1989 - 1991 南开大学,工作
1991 - 1996 中国科学院生物物理研究所,获理学博士学位
1996 - 1997 中国科学院生物物理研究所,助理研究员
1997 - 1999 德国维尔兹堡大学,博士后
1999 - 至今 中国科学院生物物理研究所,研究员
在"基因、脑和行为"的框架下,以果蝇为模型,采用分子遗传学、细胞生物学、神经电生理以及行为学相结合的方法,主要研究视觉信息处理以及学习记忆等认知行为的神经回路及细胞分子机制:
1. 视觉学习记忆的神经回路及细胞分子机制;
2. 视觉信息处理的神经机制;
3. 神经系统中长非编码RNA的功能机制。
1. Wenlan Duan#, Yihao Zhang#, Xin Zhang#, Jihua Yang, Heying Shan, Li Liu*, Hongying Wei* (2023) A visual pathway into central complex for high-frequency motion-defined bars in Drosophila. J Neurosci, 43(26):4821-4836
2. Xiaoxiao Ji#, Deliang Yuan#, Hongying Wei#, Yaxin Cheng#, Xinwei Wang, Jihua Yang, Pengbo Hu, Julia Yvonne Gestrich, Li Liu*, Yan Zhu* (2020) Differentiation of theta visual motion from Fourier motion requires LC16 and R18C12 neurons in Drosophila. iScience, 23:101041.
3. Qionglin Peng#, Yijin Wang#, Meixia Li#, DeliangYuan, Mengbo Xu, Changqing Li, Zhefeng Gong, Renjie Jiao*, Li Liu* (2016) cGMP-dependent protein kinase encoded by foraging regulates motor axon guidance in Drosophila by suppressing Lola function. J Neurosci, 36(16):4635-4646.
4. Chao Guo, Yifei Du, Deliang Yuan, Meixia Li, Haiyun Gong, Zhefeng Gong*, Li Liu* (2014) A conditioned visual orientation requires the ellipsoid body in Drosophila. Learn Mem, 22:56-63.
5. Meixia Li#, Shengyun Wen#, Xiangqian Guo, Baoyan Bai, Zhefeng Gong, Xiaojun Liu, Yijin Wang, Yanqiong Zhou, Xiaowei Chen, Li Liu*, Runsheng Chen* (2012) The novel long non-coding RNA CRG regulates Drosophila locomotor behaviour. Nucleic Acids Res, 40(22):11714-11727.
6. Zhefeng Gong*, Jianqu Liu, Chao Guo, Yanqiong Zhou, Yan Teng, Li Liu* (2010) Two pairs of neurons in central brain control Drosophila innate light preference. Science, 330:499-502.
7. Yufeng Pan, Yanqiong Zhou, Chao Guo, Haiyun Gong, Zhefeng Gong*, Li Liu* (2009) Differential roles of the fan-shaped body and the ellipsoid body in Drosophila visual pattern memory. Learn Mem, 16:289-295.
8. Zhipeng Wang#, Yufeng Pan#, Weizhe Li#, Huoqing Jiang, Lazaros Chatzimanolis, Jianhong Chang, Zhefeng Gong*, Li Liu* (2008) Visual pattern memory requires foraging function in the central complex of Drosophila. Learn Mem, 15:133-142.
9. Gang Liu#, Holger Seiler#, Ai Wen, Troy Zars, Kei Ito, Reinhard Wolf, Martin Heisenberg*, Li Liu* (2006) Distinct memory traces for two visual features in the Drosophila brain. Nature, 439:551-556.
10.Li Liu, Reinhard Wolf, Roman Ernst, Martin Heisenberg* (1999) Context generalization in Drosophila visual learning requires the mushroom bodies. Nature, 400:753-756.
(资料来源:刘力研究员,2023-08-28)