中国科学院青年创新促进会会员
2006.09 - 2010.06 湖南师范大学生命科学学院,获理学学士学位
2010.09 - 2016.06 中国科学院生物物理研究所,获理学博士学位
2016.07 - 2018.06 中国科学院生物物理研究所,博士后
2018.07 - 2019.12 中国科学院生物物理研究所,助理研究员
2020.01 - 2022.01 中国科学院生物物理研究所,副研究员
组蛋白变体H2A.Z是常规组蛋白H2A的一个变体,在各种生命过程中发挥着重要的作用,我们主要研究组蛋白变体H2A.Z在DNA复制以及转录过程中的作用机制。
1. Haizhen Long#; Liwei Zhang#; Mengjie Lv#; Zengqi Wen#; Wenhao Zhang; Xiulan Chen; Peitao Zhang; Tongqing Li; Luyuan Chang; Caiwei Jin; Guozhao Wu; Xi Wang; Fuquan Yang; Jianfeng Pei; Ping Chen; Raphael Margueron; Haiteng Deng; Mingzhao Zhu*; Guohong Li*; H2A.Z facilitates licensing and activation of early replication origins, Nature, 2020, 577(7791):576-581
2. Yan Wang#; Haizhen Long#; Juan yu#; Liping Dong#; Michel Wassef; Baowen Zhuo; Xia Li; Jicheng Zhao; Min Wang; Cuifang Liu; Zengqi Wen; Luyuan Chang; Ping Chen; Qian-fei Wang; Xueqing Xu; Raphael Margueron*; Guohong Li*; Histonevariants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3deposition and gene expression regulation in mES cells, BMC Biology, 2018, 16(107)
3. Ping Chen#, Jicheng Zhao#, Yan Wang#, Min Wang, Haizhen Long, Dan Liang, Li Huang, Zengqi Wen, Wei Li, Xia Li, Hongli Feng, Haiyong Zhao, Ping Zhu, Ming Li, Qian-fei Wang, Guohong Li (2013). "H3.3 actively marks enhancers and primes gene transcription via opening higher-ordered chromatin." Genes Dev. 27, 2109-2124 (2013)
(资料来源:龙海珍副研究员,2021-11-02)