最新重要论文(影响因子PNAS及以上)

Molecular resolution imaging by repetitive optical selective exposure,Nat Methods, 09 Sep 2019

发布时间:2019年09月09日

Nature Methods09 September, 2019,DOI:https://doi.org/10.1038/s41592-019-0544-2

Molecular resolution imaging by repetitive optical selective exposure

Lusheng Gu, Yuanyuan Li, Shuwen Zhang, Yanhong Xue, Weixing Li, Dong Li, Tao Xu & Wei Ji

Abstract

We introduce an interferometric single-molecule localization method for super-resolution fluorescence microscopy. Fluorescence molecules are located by the intensities of multiple excitation patterns of an interference fringe, providing around a twofold improvement in the localization precision compared with the conventional imaging with the same photon budget. We demonstrate this technique by resolving nanostructures down to 5 nm in size over a large 25 × 25 μm2 field of view.

文章链接:https://www.nature.com/articles/s41592-019-0544-2

相关报道:http://www.ibp.cas.cn/kyjz/zxdt/201909/t20190909_5378749.html

 

 

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