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脑与认知科学重点实验室

李昂博士研究员博士生导师

中科院生物物理所，脑与认知科学国家重点实验室，研究组长

研究方向：智能医学影像

电子邮件：al@ibp.ac.cn

电话：

通讯地址：北京市朝阳区大屯路15号（100101）

英文版个人网页：http://english.ibp.cas.cn/sourcedb/rck/EN_xsszmL/202011/t20201119_341403.html

简历：

　　2011 - 2015 哈尔滨工业大学自动化专业学士

　　2015 - 2020 中科院自动化研究所模式识别与智能系统博士

　　2019 - 2020 The Alan Turing Institute 访问

　　2020.11 - 中国科学院生物物理研究所研究员

获奖及荣誉：

社会任职：

研究方向：

　　现在，我们可以获取大规模人群的多模态神经影像、基因组和复杂表型等多维度数据。这为我们提供了前所未有的机会来理解大脑的多样性，并解码认知与心理健康的个体差异。我们的课题组致力于解决这一交叉学科问题，欢迎具有数据科学、生物学和心理学背景的有志青年加入我们，共同探索以下三个方向：1)行为与影像新范式: 研究自然场景刺激（如电影态）在功能磁共振中的动态表征，以及精神病理学结构和风险研究。2)脑影像数据挖掘: 研究多模态神经影像的数据挖掘和深度学习表征。3)跨物种跨尺度研究：如何融合人类和小动物神经影像表型以及多组学数据，以解析精神疾病的病理机制。

承担项目情况：

代表论著：

1. Ang Li*, Haiyang Liu, Xu Lei, Yini He, Qian Wu, Yan Yan, Xin Zhou, Xiaohan Tian, Yingjie Peng, Shangzheng Huang, Kaixin Li, Meng Wang, Yuqing Sun, Hao Yan, Cheng Zhang, Sheng He, Ruquan Han, Xiaoqun Wang & Bing Liu. Hierarchical fluctuation shapes a dynamic flow linked to states of consciousness. Nature Communications, 2023, 14: 3238. (Co-corresponding author)

2. Meng Wang, Hao Yan, Xiaohan Tian, Weihua Yue, Yong Liu, Lingzhong Fan, Ke Hu, Yuqing Sun, Yuxin Zhao, Jing Lou, Ming Song, Peng Li, Jun Chen, Yunchun Chen, Huaning Wang, Wenming Liu, Zhigang Li, Yongfeng Yang, Hua Guo, Luxian Lv, Jun Yan, Huiling Wang, Hongxing Zhang, Huawang Wu, Yuping Ning, Lin Lu, Dai Zhang, Ang Li*, Tianzi Jiang* & Bing Liu* Neuroimaging and multiomics reveal cross-scale circuit abnormalities in schizophrenia. Nature Mental Health, 2023, 1: 633-654. (Co-corresponding author)

3. Ang Li, Andrew Zalesky, Weihua Yue, Oliver Howes, Hao Yan, Yong Liu, Lingzhong Fan, Kirstie J Whitaker, Kaibin Xu, Guangxiang Rao, Jin Li, Shu Liu, Meng Wang, Yuqing Sun, Ming Song, Peng Li, Jun Chen, Yunchun Chen, Huaning Wang, Wenming Liu, Zhigang Li, Yongfeng Yang, Hua Guo, Ping Wan, Luxian Lv, Lin Lu, Jun Yan, Yuqing Song, Huiling Wang, Hongxing Zhang, Huawang Wu, Yuping Ning, Yuhui Du, Yuqi Cheng, Jian Xu, Xiufeng Xu, Dai Zhang, Xiaoqun Wang, Tianzi Jiang & Bing Liu. A neuroimaging biomarker for striatal dysfunction in schizophrenia. Nature Medicine, 2020, 26: 558-565.

4. Shu Liu^#, Ang Li^#, Meifang Zhu, Jin Li, Bing Liu. Genetic influences on cortical myelination in the human brain[J]. Genes, Brain and Behavior, 2019, 18(4): e12537.

5. Yan Yan, Xuankun Wu, Chengdong Li, Yini He, Zhicheng Zhang, Huihui Li, Ang Li*, Lei Wang*. Topological EEG Nonlinear Dynamics Analysis for Emotion Recognition. IEEE Transactions on Cognitive and Developmental Systems, 2022

6. Haiyang Liu, Ke Hu, Yingjie Peng, Xiaohan Tian, Meng Wang, Bo Ma, Youxuan Wu, Wanchen Sun, Bing Liu, Ang Li*, Ruquan Han*. Dynamic reconfiguration of human brain networks across altered states of consciousness. Behavioural Brain Research, 2022, 419: 113685.

7. Guangxiang Rao, Ang Li, Yong Liu, Bing Liu. A High-Powered Brain Age Prediction Model Based on Convolutional Neural Network. The IEEE International Symposium on Biomedical Imaging, 2020

8. Shu Liu, Ang Li, Yong Liu, Jin Li, Meng Wang, Yuqing Sun, Wen Qin, Chunshui Yu , Tianzi Jiang, Bing Liu. MIR137 polygenic risk is associated with schizophrenia and affects functional connectivity of the dorsolateral prefrontal cortex. Psychological Medicine, 2019: 1-9.

9. Shu Liu, Ang Li, Yong Liu, Hao Yan, Meng Wang, Yuqing Sun, Lingzhong Fan, Ming Song, Kaibin Xu, Jun Chen, Yunchun Chen, Huaning Wang, Hua Guo (a10), Ping Wan, Luxian Lv, Yongfeng Yang, Peng Li, Lin Lu , Jun Yan, Huiling Wang, Hongxing Zhang, Huawang Wu, Yuping Ning, Dai Zhang, Tianzi Jiang and Bing Liu. Polygenic effects of schizophrenia on hippocampal grey matter volume and hippocampus. The British Journal of Psychiatry, 2019: 1-8.

10. Jiachen Li, Dan Jin, Ang Li, Bing Liu, Chengyuan Song, Pan Wang, Dawei Wang, Kaibin Xu, Hongwei Yang, Hongxiang Yao, Bo Zhou, Alexandre Bejanin, Gael Chetelat, Tong Han, Jie Lu, Qing Wang, Chunshui Yu m, Xinqing Zhang, Yuying Zhou, Xi Zhang, Tianzi Jiang, Yong Liu, Ying Han. ASAF: altered spontaneous activity fingerprinting in Alzheimer's disease based on multisite fMRI. Science Bulletin, 2019

11. Jin Li, Xiaolong Zhang, Ang Li, Shu Liu, Wen Qin, Chunshui Yu, Yong Liu, Bing Liu, Tianzi Jiang. Polygenic risk for Alzheimer's disease influences precuneal volume in two independent general populations[J]. Neurobiology of aging, 2018, 64: 116-122.

12. Tianqi Wang, Xiaolong Zhang, Ang Li, Meifang Zhu, Shu Liu, Wen Qin, Jin Li, Chunshui Yu, Tianzi Jiang, Bing Liu. Polygenic risk for five psychiatric disorders and cross-disorder and disorder-specific neural connectivity in two independent populations[J]. NeuroImage: Clinical, 2017, 14: 441-449.

（资料来源：李昂研究员，2023-09-13）