脑与认知科学重点实验室

1997 - 2002   中国科学技术大学，生物科学，理学学士；计算机科学与技术（双），工学学士

2004 - 2007   中国科学院昆明动物研究所，动物学，博士

2007 - 2012   美国国立精神卫生研究所，博士后

2012 - 2016   美国国立精神卫生研究所，Research Fellow

2016.8 - 至今 中国科学院生物物理研究所脑与认知科学国家重点实验室，研究员

高效的社会沟通和互动对个体乃至群体的生存都具有极为重要的意义。正常的社会活动中所需要的一系列特定的认知活动（如面孔加工、情绪处理等）即为社会认知。社会认知功能障碍是众多脑疾病（如自闭症、精神分裂症、焦虑症等）的一个标志性特征。非人灵长类动物（特别是各方面最宜进行实验的猕猴）由于其与人类在遗传、生理、神经解剖和行为上的相似性，是研究社会认知及其障碍相关脑疾病的最佳动物模型。我们以猕猴为实验动物，结合行为猴脑功能磁共振成像技术与其他多种研究手段（如行为学、药理学、电生理、神经计算模型等），同时结合基于健康人群和脑疾病患者的观察与实验，从细胞、系统和行为等方面，多层次、多角度地研究社会认知及其相关脑疾病的神经机制，并针对相关脑疾病发展新的早期检测和有效治疗方案。

（* Corresponding Author, ^# First Author）

1. Lu X^#, Hu Z^#, Xin Y^#, Yang T, Wang Y, Zhang P, Liu N*, Jiang Y*. (2024, Nov 7) Detecting Biological Motion Signals in Human and Monkey Superior Colliculus: A Subcortical-Cortical Pathway for Biological Motion Perception. Nat Commun, 15(1), 9606. https://doi.org/10.1038/s41467-024-53968-x

2. Zhao M, Xin Y, Deng H, Zuo Z, Wang X*, Bi Y*, & Liu N*. (2024, Oct 28). Object color knowledge representation occurs in the macaque brain despite the absence of a developed language system. PLoS Biol, 22(10), e3002863. https://doi.org/10.1371/journal.pbio.3002863

3. Zhao M, Li R, Xiang S, & Liu N*. (2024, Oct 3). Two different mirror neuron pathways for social and non-social actions? A meta-analysis of fMRI studies. Soc Cogn Affect Neurosci. https://doi.org/10.1093/scan/nsae068

4. Yang Y^#, Lu X^#, Liu N^#, Ma S^#, Zhang H^#, Zhang Z^#, Yang K, Jiang M, Zheng Z, Qiao Y, Hu Q, Huang Y, Zhang Y, Xiong M, Liu L, Jiang X, Reddy P, Dong X, Xu F, Wang Q, Zhao Q, Lei J, Sun S, Jing Y, Li J, Cai Y, Fan Y, Yan K, Jing Y, Haghani A, Xing M, Zhang X, Zhu G, Song W, Horvath S, Rodriguez Esteban C, Song M, Wang S, Zhao G, Li W, Izpisua Belmonte JC, Qu J, Zhang W, & Liu G. (2024, Sep 12). Metformin decelerates aging clock in male monkeys. Cell. https://doi.org/10.1016/j.cell.2024.08.021

5.Liu N*, Avidan G, Turchi JN, Hadj-Bouziane F, & Behrmann M. (2024, Jun 26). A Possible Neural Basis for Attentional Capture of Faces Revealed by Functional Magnetic Resonance Imaging and Causal Pharmacological Inactivation in Macaques. J Cogn Neurosci, 1-19. https://doi.org/10.1162/jocn_a_02211

6. Zhang Z, Dong X, Liu Z, & Liu N*. (2024, Jun 21). Social status predicts physiological and behavioral responses to chronic stress in rhesus monkeys. iScience, 27(6). https://doi.org/10.1016/j.isci.2024.110073

7. Zhang Q, Zhang Y, Liu N*, & Sun X*. (2024, Apr 9). Understanding of facial features in face perception: insights from deep convolutional neural networks. Front Comput Neurosci, 18. https://doi.org/10.3389/fncom.2024.1209082

8. Wu Y^#, Zhao M^#, Deng H, Wang T, Xin Y, Dai W, Huang J, Zhou T, Sun X, Liu N*, & Xing D*. (2024, Jan 15). The neural origin for asymmetric coding of surface color in the primate visual cortex. Nat Commun, 15(1), 516. https://doi.org/10.1038/s41467-024-44809-y

9. Sun F, Yang T, Liu N*, & Wan X*. (2023, Oct 13). The causal role of temporoparietal junction in mediating self-other mergence during mentalizing. J Neurosci. https://doi.org/10.1523/JNEUROSCI.1026-23.2023

10. Xiang S^#, Zhao M^#, Yu L, & Liu N*. (2023, Aug 11). A common self-advantage across the implicit and explicit levels for self-body recognition. Front Psychol, 14, 1099151. https://doi.org/10.3389/fpsyg.2023.1099151

11. Zhang H*, Ding X, Liu N, Nolan R, Ungerleider LG, & Japee S. (2023, Jun). Equivalent processing of facial expression and identity by macaque visual system and task-optimized neural network. Neuroimage, 273, 120067. https://doi.org/10.1016/j.neuroimage.2023.120067

12. Cui S, Yang T, & Liu N*. (2023, Jun 15). Generalization of the modulatory effect of social interaction on personal space. Front Psychol, 14, 1148395. https://doi.org/10.3389/fpsyg.2023.1148395

13. Shen B, Zhang Z, Wang Q, Tu Z*, Liu N*. (2023, May 25) A new approach to detecting and analyzing monkey activities using the improved YOLOv5. Third International Conference on Machine Learning and Computer Application (ICMLCA 2022).

14. Xin Y^#, Bai T^#, Zhang T, Chen Y, Wang K, Yu S*, Liu N*, & Tian Y*. (2022, Jan-Feb). Electroconvulsive therapy modulates critical brain dynamics in major depressive disorder patients. Brain Stimul, 15(1), 214-225. https://doi.org/10.1016/j.brs.2021.12.008

15.Liu N*, Behrmann M, Turchi JN, Avidan G, Hadj-Bouziane F, & Ungerleider LG. (2022, Nov 9). Bidirectional and parallel relationships in macaque face circuit revealed by fMRI and causal pharmacological inactivation. Nat Commun, 13(1), 6787. https://doi.org/10.1038/s41467-022-34451-x

16. Li N, & Liu N*. (2021, Jul 14). The Nonlinear and Gender-Related Relationships of Face Attractiveness and Typicality With Perceived Trustworthiness. Front Psychol, 12, 656084. https://doi.org/10.3389/fpsyg.2021.656084

17. Meng Q*, Wang B, Cui D, Liu N, Huang Y*, Chen L, & Ma Y. (2019, Jan 2). Age-related changes in local and global visual perception. J Vis, 19(1), 10. https://doi.org/10.1167/19.1.10

18. Taubert J*, Flessert M, Liu N, & Ungerleider LG. (2019, Oct 23). Intranasal oxytocin selectively modulates the behavior of rhesus monkeys in an expression matching task. Sci Rep, 9(1), 15187. https://doi.org/10.1038/s41598-019-51422-3

19. Tomeo OB, Ungerleider LG, & Liu N*. (2017, Jul 11). Preference for Averageness in Faces Does Not Generalize to Non-Human Primates. Front Behav Neurosci, 11, 129. https://doi.org/10.3389/fnbeh.2017.00129

加入生物物理所之前

20. Zhang H*, Japee S, Nolan R, Chu C, Liu N, & Ungerleider LG. (2016, Apr 15). Face-selective regions differ in their ability to classify facial expressions. Neuroimage, 130, 77-90. https://doi.org/10.1016/j.neuroimage.2016.01.045

21.Liu N, Hadj-Bouziane F, Moran, R, Ungerleider LG, & Ishai A*. (2016, Jan 11). Facial Expressions Evoke Differential Neural Coupling in Macaques. Cereb Cortex. https://doi.org/10.1093/cercor/bhv345

22.Liu N*, Hadj-Bouziane F, Jones, K. B, Turchi JN, Averbeck BB, & Ungerleider LG*. (2015, Jun 16). Oxytocin modulates fMRI responses to facial expression in macaques. Proc Natl Acad Sci U S A, 112(24), E3123-3130. https://doi.org/10.1073/pnas.1508097112

23. Avidan G*, Tanzer M, Hadj-Bouziane F, Liu N, Ungerleider LG, & Behrmann M. (2014, Jun). Selective dissociation between core and extended regions of the face processing network in congenital prosopagnosia. Cereb Cortex, 24(6), 1565-1578. https://doi.org/10.1093/cercor/bht007

24.Liu N*, Kriegeskorte N, Mur M, Hadj-Bouziane F, Luh WM, Tootell RB, & Ungerleider LG. (2013, Jul 10). Intrinsic structure of visual exemplar and category representations in macaque brain. J Neurosci, 33(28), 11346-11360. https://doi.org/10.1523/JNEUROSCI.4180-12.2013

25. Hadj-Bouziane F, Liu N, Bell, A. H, Gothard, K. M, Luh, W. M, Tootell RB, Murray EA, & Ungerleider LG. (2012, Dec 26). Amygdala lesions disrupt modulation of functional MRI activity evoked by facial expression in the monkey inferior temporal cortex. Proc Natl Acad Sci U S A, 109(52), E3640-3648. https://doi.org/10.1073/pnas.1218406109

26. Furl N^#, Hadj-Bouziane F^#, Liu N, Averbeck BB, & Ungerleider LG. (2012, Nov 7). Dynamic and static facial expressions decoded from motion-sensitive areas in the macaque monkey. J Neurosci, 32(45), 15952-15962. https://doi.org/10.1523/JNEUROSCI.1992-12.2012

27. Talbot T*, Ide D, Liu N, & Turchi J. (2011, Dec 4). A novel, variable angle guide grid for neuronal activity studies. Front Integr Neurosci, 6, 1. https://doi.org/10.3389/fnint.2012.00001

28. Nasr S, Liu N, Devaney KJ, Yue X, Rajimehr R, Ungerleider LG, & Tootell RB. (2011, Sep 28). Scene-selective cortical regions in human and nonhuman primates. J Neurosci, 31(39), 13771-13785. https://doi.org/10.1523/JNEUROSCI.2792-11.2011

29. Wu CW, Vasalatiy O, Liu N, Wu H, Cheal S, Chen DY, Koretsky AP, Griffiths GL, Tootell RB, & Ungerleider LG. (2011, Apr 28). Development of a MR-visible compound for tracing neuroanatomical connections in vivo. Neuron, 70(2), 229-243. https://doi.org/10.1016/j.neuron.2011.03.010

（资料来源：刘宁研究员，2024-11-11）