1997 - 2001 南京大学基础教学强化部，获理学学士学位

　　2001 - 2006 清华大学医学院，获生物物理学博士学位

　　2006 - 至今 中国科学院生物物理研究所，研究员；课题组组长；蛋白质科学研究平台生物成像中心首席科学家(兼主任)。

　　2018.1-至今 中国科学院大学, 生命科学学院, 长江青年学者

　　主要研究方向

　　综合多种结构生物学研究手段（以低温电镜技术和X射线晶体学技术为主）并发展新的结构研究技术方法，在多尺度上（从纳观到介观）和多层次上（体外和体内），来研究生物系统的高分辨率构造。主要研究内容包括：线粒体动态的分子机制，重要膜蛋白的结构与功能，以及生物显微成像方法学（主要是图像处理算法）研究。

　　代表性论文及论著

　　1. Huang X.#, Zhang L.#, Wen Z., Chen H., Li S., Ji G., Yin C.C. and Sun F.* (2020) Amorphous nickel titanium alloy film: a new choice for cryo electron microscopy sample preparation. Progress in Biophysics and Molecular Biology. doi: 10.1016/j.pbiomolbio.2020.07.009 [Epub ahead of print]

　　2. Lu J.#, Chan C.#, Yu L.#, Fan J.*, Sun F.* and Zhai Y.* (2020) Molecular mechanism of mitochondrial phosphatidate transfer by Ups1. Communications Biology, 3: 468. doi: 10.1038/s42003-020-01121-x

　　3. Shi Y.#, Xin Y.#, Wang C.#, Blankenship R.E., Sun F.* and Xu XL.* (2020) Cryo-EM structure of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii. Science Advances, 6 (31): eaba2739. doi: 10.1126/sciadv.aba2739

　　4. Xia S., Liu M., Wang C., Xu W., Lan Q., Feng S., Qi F., Bao L., Du L., Liu S., Qin C., Sun F.&, Shi Z.&, Zhu Y.*&, Jiang S.*&, and Lu L.*& (2020) Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell Research, 30 (4): 343-355. doi: 10.1038/s41422-020-0305-x. (&: co-senior authors)

　　5. Zhang D., Zhang Y., Ma J., Zhu C., Niu T., Chen W., Pang X., Zhai Y., and Sun F.* (2020) Cryo-EM structures of S-OPA1 reveal its interactions with membrane and changes upon nucleotide binding. eLife 9: e50294. doi: 10.7554/eLife.50294

　　6. Qiao A., Han S., Li X., Li Z., Zhao P., Dai A., Chang R., Tai L., Tan Q., Chu X., Ma L., Thorsen T.S., Reedtz-Runge S., Yang D., Wang M., Sexton P.M., Wootten D., Sun F.*, Zhao Q.*, and Wu B.* (2020) Structural basis of Gs and Gi recognition by the human glucagon receptor. Science, 367: 1346-1352. doi: 10.1126/science.aaz5346.

　　7. Zhu G., Zeng H., Zhang S., Juli J., Pang X., Hoffmann J., Zhang Y., Morgner N., Zhu Y.*, Peng G.*, Michel H.* and Sun F.* (2020) A 3.3 A-resolution structure of hyperthermophilic respiratory complex III reveals the mechanism of its thermal stability. Angew Chem Int Ed Engl. 59 (1): 343-351. doi: 10.1002/anie.201911554

　　8. Ren Z., Zhang Y., Zhang Y., He Y., Du P., Wang Z., Sun F.* and Ren H.* (2019) Cryo-EM structure of actin filaments from Zea mays pollen. Plant Cell. pii: tpc.00973.2018. doi: 10.1105/tpc.18.00973.

　　9. Li X., Zhang S., Zhang J. and Sun F.* (2018), In situ protein micro-crystal fabrication by cryo-FIB for electron diffraction. Biophysics Reports, 4(6): 339-347. doi: 10.1007/s41048-018-0075-x.

　　10. Gong H., LI L., Xu A., Tang Y., Ji W., Gao R., Wang S., Yu L., Tian C., Li J., Yen H.Y., Lam S.M., Shui G., Yang X., Sun Y., Li X., Jia M., Yang C., Jiang B., Lou Z., Robinson C., Wong L.L., Guddat L.W., Sun F.*, Wang Q.* and Rao Z.* (2018), A electron transfer path connects subunits of a mycobacterial respiratory supercomplex. Science 362(6418), pii: eaat8923. doi: 10.1126/science.aat8923.

　　11. Xin Y., Shi Y., Niu T., Wang Q., Niu W., Huang X., Ding W., Yang L., Blankenship R. E., Xu X.* and Sun F.* (2018) Cryo-EM structure of the RC-LH core complex from an early branching photosynthetic prokaryote. Nature communications, 9:1568. doi: 10.1038/s41467-018-03881-x.

　　12. Li S., Ji G.*, Shi Y., Klausen L.H., Niu T., Wang S., Huang X., Ding W., Zhang X., Dong M., Xu W., and Sun F.* (2018), High-vacuum optical platform for cryo-CLEM(HOPE): a new solution for non-integrated multiscale correlative light and electron microscopy. Journal of Structural Biology, 201(1): 63-75.

　　13. Lu G., Xu Y., Zhang K., Xiong Y., Li H., Cui L., Wang X., Lou J., Zhai Y.*, Sun F.* and Zhang X.C.* (2017), Crystal structure of E. coli apolipoprotein N-acyltransferase. Nature Communications, 8:15948.

　　14. Chen R., Gao B., Liu, X., Ruan F., Zhang Y., Lou J., Feng K., Wunsch C., Li S.M., Dai J.* and Sun F.* (2016), Molecular insights into the enzyme promiscuity of an aromatic prenyltransferase. Nature Chemical Biology (Advanced online at Dec. 19, 2016)

　　15. Wei R., Wang X., Zhang Y., Mukherjee S., Zhang L., Chen Q., Huang X., Jing S., Liu C., Li S., Wang G., Xu Y., Zhu S., Williams A., Sun F.* and Yin C.C.* (2016), Structural insights into Ca2+ -activated long-range allosteric channel gating of RyR1. Cell Research 26: 977-994 (Cover story).